GW29-e0040 Knowledge Assessment of Cardiovascular Diseases among Pakistani Population

Estimating the mutational load for cardiovascular diseases in Pakistani population

The deleterious genetic variants contributing to certain diseases may differ in terms of number and allele frequency from population to population depending on their evolutionary background. Here, we prioritize the deleterious variants from Pakistani population in manually curated gene list already reported to be associated with common, Mendelian, and congenital cardiovascular diseases (CVDs) u...

Evaluation of Self-assessment in Cardiovascular Diseases Among Korean Older Population

Cardiovascular diseases (CVDs) are the leading diseases in terms of morbidity and mortality in most developed and developing countries [1e3]. In accompaniment with a rapidly growing elderly population, Korea has been experiencing a sharp increase in CVDs. The prevalence of CVD risk factors such as hypertension (HTN), diabetes mellitus (DM), and hypercholesterolemia among adults (aged 30 years) ...

Genetic Polymorphism of CYP2C19 in Pakistani Population

CYP2C19 polymorphism is associated with pretreatment drug response prediction, metabolism, and disposition. Pakistan consists of a population comprising of various ethnic groups residing in different regions of the country each claiming diverse ethnic origins. The identification of CYP450 genotypic composition of these populations is therefore necessary to avoid adverse drug reactions in these ...

Prevalence of Gynaecomastia in Male Pakistani Population

Genetic Polymorphism of CYP2C19 in Pakistani Population

CYP2C19 polymorphism is associated with pretreatment drug response prediction, metabolism, and disposition. Pakistan consists of a population comprising of various ethnic groups residing in different regions of the country each claiming diverse ethnic origins. The identification of CYP450 genotypic composition of these populations is therefore necessary to avoid adverse drug reactions in these ...